4-Fluoro-3-nitrobenzyl alcohol

Base Information

Chemical Name:4-Fluoro-3-nitrobenzyl alcohol
CAS No.:20274-69-5
Molecular Formula:C7H6FNO3
Molecular Weight:171.128
Hs Code.:2906299090
European Community (EC) Number:626-903-5
DSSTox Substance ID:DTXSID20400189
Nikkaji Number:J1.599.586F
Wikidata:Q72475310
Mol file:20274-69-5.mol

Synonyms:4-Fluoro-3-nitrobenzyl alcohol;20274-69-5;(4-fluoro-3-nitrophenyl)methanol;Benzenemethanol, 4-fluoro-3-nitro-;MFCD01861396;4-Fluoro-3-nitro-benzyl alcohol;4-Fluoro-3-nitrobenzylalcohol;2-(4-Fluoro-3-nitrophenyl)propan-2-ol;1934670-90-2;3,4-DinitrobenzoicAcid;SCHEMBL545367;3-Nitro-4-fluorobenzenemethanol;4-Fluoro-3-nitrobenzenemethanol;DTXSID20400189;(4-Fluoro-3-nitro-phenyl)-methanol;AB3791;AKOS005063918;4-Fluoro-3-nitrobenzyl alcohol, 96%;AC-9744;AM62590;CS-W017657;4-FLUORO-3-NITROBENZYLALCOHOL96;AS-19058;SY107425;FT-0655509;A22656;EN300-132742;J-013169

Suppliers and Price of 4-Fluoro-3-nitrobenzyl alcohol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Fluoro-3-nitrobenzyl alcohol
25g
$ 525.00

SynQuest Laboratories
4-Fluoro-3-nitrobenzyl alcohol
25 g
$ 592.00

SynQuest Laboratories
4-Fluoro-3-nitrobenzyl alcohol
1 g
$ 112.00

SynQuest Laboratories
4-Fluoro-3-nitrobenzyl alcohol
5 g
$ 168.00

Sigma-Aldrich
4-Fluoro-3-nitrobenzyl alcohol 96%
5g
$ 121.00

Crysdot
4-Fluoro-3-nitrobenzyl alcohol 98%
100g
$ 752.00

Crysdot
4-Fluoro-3-nitrobenzyl alcohol 98%
25g
$ 99.00

Crysdot
4-Fluoro-3-nitrobenzyl alcohol 98%
10g
$ 62.00

ChemScene
4-Fluoro-3-nitrobenzyl alcohol
5g
$ 60.00

ChemScene
4-Fluoro-3-nitrobenzyl alcohol
10g
$ 110.00

Total 46 raw suppliers

Chemical Property of 4-Fluoro-3-nitrobenzyl alcohol

Chemical Property:

Vapor Pressure:5.3E-05mmHg at 25°C
Melting Point:39-44 °C(lit.)
Refractive Index:1.571
Boiling Point:333.7 °C at 760 mmHg
PKA:13.37±0.10(Predicted)
Flash Point:155.6 °C
PSA：66.05000
Density:1.434 g/cm³
LogP:1.74940
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:171.03317122
Heavy Atom Count:12
Complexity:171

Purity/Quality:

98% ^*data from raw suppliers

4-Fluoro-3-nitrobenzyl alcohol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CO)[N+](=O)[O-])F
Uses 4-Fluoro-3-nitrobenzyl Alcohol is used as a reagent in the preparation of EW-7197 (E950000) which is a highly potent orally bioavailable inhibitor of TGF-β type I receptor kinase that is used in cancer treatment as an immunotherapeutic or antifibrotic agent. 4-Fluoro-3-nitrobenzyl alcohol may be used in the synthesis of 4-fluoro-3-nitrobenzyl chloride.

Technology Process of 4-Fluoro-3-nitrobenzyl alcohol

There total 8 articles about 4-Fluoro-3-nitrobenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.1%

: 453-71-4
3-nitro-4-fluorobenzoic acid

: 20274-69-5
(4-fluoro-3-nitrophenyl)methanol

Guidance literature:: 3-nitro-4-fluorobenzoic acid; With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 1h;

With boron trifluoride diethyl etherate; In tetrahydrofuran; at 0 - 20 ℃; for 3h;