2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

Base Information

Chemical Name:2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride
CAS No.:74444-78-3
Molecular Formula:C₁₃H₁₈ClNO₂*ClH
Molecular Weight:292.205
Hs Code.:

Synonyms:2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

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Chemical Property of 2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

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Technology Process of 2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

There total 4 articles about 2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 7424-00-2,1991-78-2
DL-Phe(4Cl)

: 71-36-3
butan-1-ol

: 74444-78-3
2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; Heating;

Reference yield:

: 23633-07-0,123053-23-6,51274-82-9
2-amino-3-(4-chlorophenyl)propionic acid hydrochloride

: 71-36-3
butan-1-ol

: 74444-78-3
2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; In water; for 1h; Reflux;
DOI:10.1016/j.tet.2014.02.012

Reference yield:

: 20877-13-8
ethyl 2-acetylamino-3-(4-chlorophenyl)-2-cyanopropanoate

: 74444-78-3
2-Amino-3-(4-chloro-phenyl)-propionic acid butyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; water / 30 h / Reflux

2: hydrogenchloride / water / 1 h / Reflux

With hydrogenchloride; water; In water;
DOI:10.1016/j.tet.2014.02.012