2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical

Base Information

• Chemical Name: 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical
• CAS No.: 906465-15-4
• Molecular Formula: C₂₃H₃₆N₃O₄
• Molecular Weight: 418.557
• Mol file: 906465-15-4.mol

Synonyms:2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical

Chemical Property of 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical

There total 1 articles about 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

3-(bromomethyl)-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-oxyl (76893-32-8) + 1-(2,3,4-trimethoxybenzyl)piperazine (5011-34-7) → 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical (906465-15-4)

Guidance literature:

With potassium carbonate; In chloroform; for 3h; Heating;

DOI:10.1016/j.bmc.2006.04.040

Reference yield: 73.0%

2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical (906465-15-4) → 1-hydroxy-2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrole trihydrochloride

Guidance literature:

With hydrogenchloride; In ethanol; for 0.5h; Heating;

DOI:10.1016/j.bmc.2006.04.040

Reference yield: 39.0%

2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrol-1-yloxyl radical (906465-15-4) → 2,2,5,5-tetramethyl-3-[4-(2,3,4-trimethoxybenzyl)piperazin-1-ylmethyl]-2,5-dihydro-1H-pyrrole

Guidance literature:

With iron; acetic acid; at 70 ℃; for 1h;

DOI:10.1016/j.bmc.2006.04.040

upstream raw materials:

3-(bromomethyl)-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-oxyl

1-(2,3,4-trimethoxybenzyl)piperazine