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C22H35F2NO2

Base Information
  • Chemical Name:C22H35F2NO2
  • CAS No.:1373945-60-8
  • Molecular Formula:C22H35F2NO2
  • Molecular Weight:383.522
  • Hs Code.:
C<sub>22</sub>H<sub>35</sub>F<sub>2</sub>NO<sub>2</sub>

Synonyms:C22H35F2NO2

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Chemical Property of C22H35F2NO2
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Technology Process of C22H35F2NO2

There total 1 articles about C22H35F2NO2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
2-hydroxypalmitic acid; With 1,2,4-Triazole; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;
N-sulfinyl-2.6-difluoroaniline; In dichloromethane; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1021/ol300922b
Guidance literature:
With sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol300922b
Guidance literature:
Multi-step reaction with 2 steps
1.1: sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 20 °C / Inert atmosphere
2.1: toluene / 16 h / Reflux; Inert atmosphere
2.2: 5 h / Reflux; Inert atmosphere
With sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide; toluene; 2.1: iso-Pictet-Spengler reaction / 2.2: iso-Pictet-Spengler reaction;
DOI:10.1021/ol300922b
upstream raw materials:

2-hydroxypalmitic acid

N-sulfinyl-2.6-difluoroaniline

Downstream raw materials:

C22H33F2NO2

C32H43F2N3O

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