C₃₃H₂₇N₃O₃

Base Information

• Chemical Name: C₃₃H₂₇N₃O₃
• CAS No.: 1376947-95-3
• Molecular Formula: C₃₃H₂₇N₃O₃
• Molecular Weight: 513.596
• Mol file: 1376947-95-3.mol

Synonyms:C₃₃H₂₇N₃O₃

Chemical Property of C₃₃H₂₇N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₂₇N₃O₃

There total 4 articles about C₃₃H₂₇N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

C33H25N3O4 (1376947-92-0) → C33H27N3O3 (1376947-95-3)

Guidance literature:

With sodium tetrahydroborate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h;

DOI:10.1016/j.tet.2011.11.066

Reference yield:

N-ethoxycarbonylphthalimide (22509-74-6) → C33H27N3O3 (1376947-95-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium carbonate / water / 3 h

1.2: 0 - 20 °C

1.3: 2 h / 50 °C

2.1: sodium tetrahydroborate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 0 °C

With sodium tetrahydroborate; sodium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In water; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2011.11.066

Reference yield:

trityl chloride (76-83-5) → C33H27N3O3 (1376947-95-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium carbonate / water / 3 h

1.2: 0 - 20 °C

1.3: 2 h / 50 °C

2.1: sodium tetrahydroborate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 0 °C

With sodium tetrahydroborate; sodium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In water; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2011.11.066

upstream raw materials:

C₃₃H₂₅N₃O₄

N-ethoxycarbonylphthalimide

trityl chloride

L-histidine

Downstream raw materials:

C₃₃H₂₆N₆O₂

C₃₄H₂₉N₃O₅S