(S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

Base Information

Chemical Name:(S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea
CAS No.:1114451-32-9
Molecular Formula:C₂₆H₃₀N₂O₃S
Molecular Weight:450.602
Hs Code.:

Synonyms:(S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

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Technology Process of (S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

There total 2 articles about (S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1114451-23-8
1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(benzoyl)phenyl)-1,3-dimethylurea

: 1114451-32-9
(S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; diastereoselective reaction; Inert atmosphere;
DOI:10.1039/b817527f

Reference yield:

: 1114451-23-8
1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(benzoyl)phenyl)-1,3-dimethylurea

: 1114451-32-9
(S,R)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

: 1114451-22-7
(S,S)-1-(2-(tert-butylsulfinyl)phenyl)-3-(2-(hydroxy(phenyl)methyl)phenyl)-1,3-dimethylurea

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; Reagent/catalyst; Solvent; optical yield given as %de; diastereoselective reaction; Reactivity; Inert atmosphere;
DOI:10.1039/b817527f