2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene

Base Information

• Chemical Name: 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene
• CAS No.: 255839-60-2
• Molecular Formula: C₃₉H₇₅BrSi₈
• Molecular Weight: 848.612
• Mol file: 255839-60-2.mol

Synonyms:2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene

Chemical Property of 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene

There total 4 articles about 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-1,2-dihydro-2-silanaphthalene (255839-39-5) → 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene (255839-60-2)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane; for 120h;

DOI:10.1021/ja992024f

Reference yield:

1,2,3,4-tetrahydro-2-silanaphthalene (4667-93-0) → 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene (255839-60-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

1.2: tetrahydrofuran / 10 h / -78 - 20 °C

3.1: 98 percent / NBS / CCl₄ / 120 h

With N-Bromosuccinimide; tert.-butyl lithium; In tetrahydrofuran; tetrachloromethane; pentane; 1.1: Metallation / 1.2: Substitution / 3.1: Bromination;

DOI:10.1021/ja992024f

Reference yield:

2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-1,2,3,4-tetrahydro-2-silanaphthalene (255839-47-5) → 2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-2-bromo-1,2-dihydro-2-silanaphthalene (255839-60-2)

Guidance literature:

Multi-step reaction with 2 steps

2: 98 percent / NBS / CCl₄ / 120 h

With N-Bromosuccinimide; In tetrachloromethane; 2: Bromination;

DOI:10.1021/ja992024f

upstream raw materials:

2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-1,2-dihydro-2-silanaphthalene

1,2,3,4-tetrahydro-2-silanaphthalene

2-{2,6-bis[bis(trimethylsilyl)methyl]-4-[tris(trimethylsilyl)methyl]phenyl}-1,2,3,4-tetrahydro-2-silanaphthalene

1,2,3,4-tetrahydro-2,2-dichloro-2-silanaphthalene