3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide

Base Information

Chemical Name:3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide
CAS No.:70751-13-2
Molecular Formula:C₁₂H₁₁ClN₄O₂
Molecular Weight:278.698
Hs Code.:
DSSTox Substance ID:DTXSID801176543
Nikkaji Number:J3.595.803G

Synonyms:DTXSID801176543;3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide;70751-13-2

Suppliers and Price of 3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:278.0570533
Heavy Atom Count:19
Complexity:427

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NN(C(=O)C=C2)CC(=O)NN)Cl

Technology Process of 3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide

There total 6 articles about 3-(4-Chlorophenyl)-6-oxo-1(6H)-pyridazineacetic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70751-11-0
ethyl 2-(3-(4-chlorophenyl)-6-oxopyridazin-1(6H)-yl)acetate

: 70751-13-2
2-[6-(4-chlorophenyl)-3-oxo-2H-pyridazin-2-yl]acetohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 3h; Reflux;
DOI:10.2174/1570180811310060006

Reference yield:

: 99-91-2
para-chloroacetophenone

: 70751-13-2
2-[6-(4-chlorophenyl)-3-oxo-2H-pyridazin-2-yl]acetohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2 h / 100 - 105 °C

1.2: 2 h / pH 8 / Reflux

2.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

3.1: hydrazine hydrate / ethanol / 3 h / Reflux

With hydrazine hydrate; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/1570180811310060006

Reference yield:

: 2166-13-4
6-(p-chlorophenyl)-3(2H)-pyridazinone

: 70751-13-2
2-[6-(4-chlorophenyl)-3-oxo-2H-pyridazin-2-yl]acetohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

2: hydrazine hydrate / ethanol / 3 h / Reflux

With hydrazine hydrate; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/1570180811310060006