Technology Process of (S)-2-amino-3,3-dimethyl butane salt of rosuvastatin
There total 1 articles about (S)-2-amino-3,3-dimethyl butane salt of rosuvastatin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
acetonitrile;
at 20 ℃;
- Guidance literature:
-
(S)-2-amino-3,3-dimethyl butane salt of rosuvastatin;
With
hydrogenchloride;
In
water; ethyl acetate;
at 5 - 10 ℃;
for 0.25h;
pH=3 - 4;
With
sodium hydroxide;
In
tert-butyl methyl ether; water;
at 15 - 20 ℃;
for 0.5h;
pH=9.0 - 11.5;
With
calcium acetate;
In
tert-butyl methyl ether; water;
at 20 - 25 ℃;
