4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine

Base Information

Chemical Name:4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine
CAS No.:71149-52-5
Molecular Formula:C7H6ClN3
Molecular Weight:167.598
Hs Code.:2933990090
European Community (EC) Number:875-434-4
DSSTox Substance ID:DTXSID70448334
Nikkaji Number:J1.546.603K
Wikidata:Q72455104
Mol file:71149-52-5.mol

Synonyms:4-CHLORO-2-METHYL-7H-PYRROLO[2,3-D]PYRIMIDINE;71149-52-5;4-Chloro-2-methyl-1H-pyrrolo[2,3-d]pyrimidine;MFCD09746275;1H-PYRROLO[2,3-D]PYRIMIDINE, 4-CHLORO-2-METHYL-;SCHEMBL3011647;AMY6980;DTXSID70448334;HCFJHJBEGJJOMO-UHFFFAOYSA-N;AKOS006330362;AKOS015951437;AB51256;CS-W008222;AC-22318;DS-10988;SY046593;A9337;FT-0649443;EN300-94330;2-Methyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidine;J-514966;Z1696822330;4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine, AldrichCPR

Suppliers and Price of 4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine
50mg
$ 45.00

SynQuest Laboratories
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 95%
1 g
$ 136.00

SynQuest Laboratories
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 95%
25 g
$ 952.00

SynQuest Laboratories
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 95%
5 g
$ 296.00

Sigma-Aldrich
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine Aldrich
1g
$ 610.00

Matrix Scientific
4-Chloro-2-methyl-1H-pyrrolo[2,3-d]pyrimidine 95%
5g
$ 1599.00

Matrix Scientific
4-Chloro-2-methyl-1H-pyrrolo[2,3-d]pyrimidine 95%
1g
$ 533.00

Matrix Scientific
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 95+%
5g
$ 164.00

Matrix Scientific
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 95+%
1g
$ 49.00

Crysdot
4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine 98%
25g
$ 190.00

Total 78 raw suppliers

Chemical Property of 4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine

Chemical Property:

Vapor Pressure:0.102mmHg at 25°C
Melting Point:207-208 °C
Refractive Index:1.688
Boiling Point:229.938 °C at 760 mmHg
PKA:11.49±0.20(Predicted)
Flash Point:114.932 °C
PSA：41.57000
Density:1.438 g/cm³
LogP:1.91970
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:167.0250249
Heavy Atom Count:11
Complexity:153

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C=CN2)C(=N1)Cl

Technology Process of 4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine

There total 6 articles about 4-Chloro-2-methyl-7H-pyrrolo[2,3-D]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

: 89792-11-0
2-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one

: 71149-52-5
4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With tetraethylammonium chloride; trichlorophosphate; at 60 - 80 ℃; for 0.5h;

Reference yield: 85.0%

: 1314922-47-8
2-methyl-4-hydroxypyrrolo[2,3-d]pyrimidine

: 71149-52-5
4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With trichlorophosphate; for 2h; Reflux;

Reference yield: 82.0%

: 2-methyl-4(3H)-oxo-7H-pyrrolo<2,3-d>pyrimidine

: 71149-52-5
4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate; In acetonitrile; at 100 ℃;
DOI:10.1021/jm4018948