2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline

Base Information

Chemical Name:2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline
CAS No.:250592-89-3
Molecular Formula:C₁₀H₁₂N₂O
Molecular Weight:176.218
Hs Code.:
European Community (EC) Number:607-516-0
DSSTox Substance ID:DTXSID501237409

Synonyms:2-(4,5-dihydroisoxazol-3-yl)-3-methylaniline;250592-89-3;SCHEMBL700713;HFWVJEXKJBOUHJ-UHFFFAOYSA-N;DTXSID501237409;2-(4,5-dihydroisoxazol-3-yl) -3-methylaniline;2-(4,5-Dihydro-3-isoxazolyl)-3-methylbenzenamine

Suppliers and Price of 2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:215

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)N)C2=NOCC2

Technology Process of 2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline

There total 3 articles about 2-(4,5-Dihydroisoxazol-3-yl)-3-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: 250592-88-2
3-((2-methyl)-6-nitrophenyl)-4,5-dihydroisoxazole

: 250592-89-3
3-(2-methyl-6-aminophenyl)-4,5-dihydroisoxazole

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In dichloromethane; at 25 - 30 ℃; for 10h;

Reference yield:

: 2-methyl-6-nitrosobenzaldehyde oxime

: 250592-89-3
3-(2-methyl-6-aminophenyl)-4,5-dihydroisoxazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid; chlorine / 4 h / Inert atmosphere

1.2: 24 h / 6000.6 - 7500.75 Torr

2.1: 5%-palladium/activated carbon; hydrogen / dichloromethane / 10 h / 25 - 30 °C

With 5%-palladium/activated carbon; hydrogen; chlorine; acetic acid; In dichloromethane;

Reference yield:

: 83-41-0
2,3-dimethylnitrobenzene

: 250592-89-3
3-(2-methyl-6-aminophenyl)-4,5-dihydroisoxazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: nitroso isopentyl ester; sodium methylate / N,N-dimethyl-formamide / 0.5 h / -40 - -35 °C

2.1: acetic acid; chlorine / 4 h / Inert atmosphere

2.2: 24 h / 6000.6 - 7500.75 Torr

3.1: 5%-palladium/activated carbon; hydrogen / dichloromethane / 10 h / 25 - 30 °C

With 5%-palladium/activated carbon; nitroso isopentyl ester; hydrogen; sodium methylate; chlorine; acetic acid; In dichloromethane; N,N-dimethyl-formamide;