Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester

Base Information

• Chemical Name: Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester
• CAS No.: 73640-25-2
• Molecular Formula: C₄₂H₆₆N₄O₇
• Molecular Weight: 739.009
• Mol file: 73640-25-2.mol

Synonyms:Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester

Chemical Property of Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester

There total 4 articles about Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

eicosanoyl chloride (40140-09-8) + 1-glycerol (73640-37-6) → Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester (73640-25-2)

Guidance literature:

With pyridine; In 1,4-dioxane; at 10 ℃; for 4.25h;

DOI:10.1021/ja00527a004

Reference yield:

6-bromohexanoyl chloride (22809-37-6) → Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester (73640-25-2)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / CHCl₃

3: 1.) conc. HCl, NaNO₂

4: pyridine / dioxane / 4.25 h / 10 °C

With pyridine; hydrogenchloride; sodium nitrite; In 1,4-dioxane; chloroform;

DOI:10.1021/ja00527a004

Reference yield:

(2,3-O-isopropylidene)propyl 6-bromohexanoate → Icosanoic acid 2-hydroxy-3-(6-{methyl-[4-(4-nitro-phenylazo)-phenyl]-amino}-hexanoyloxy)-propyl ester (73640-25-2)

Guidance literature:

Multi-step reaction with 3 steps

2: 1.) conc. HCl, NaNO₂

3: pyridine / dioxane / 4.25 h / 10 °C

With pyridine; hydrogenchloride; sodium nitrite; In 1,4-dioxane;

DOI:10.1021/ja00527a004

upstream raw materials:

eicosanoyl chloride

1-glycerol

6-bromohexanoyl chloride