Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate

Base Information

• Chemical Name: Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate
• CAS No.: 128678-22-8
• Molecular Formula: C₄₀H₄₈Cl₆O₂₀Si
• Molecular Weight: 1089.61
• Mol file: 128678-22-8.mol

Synonyms:Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate

Chemical Property of Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate

There total 1 articles about Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H42O14Si (128678-20-6) + Chloroacetic anhydride (541-88-8) → Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate (128678-22-8)

Guidance literature:

With 2,6-dimethylpyridine; triethylamine; In dichloromethane;

DOI:10.1016/0008-6215(90)84106-5

Reference yield: 95.0%

Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate (128678-22-8) + acetic anhydride (108-24-7) → Benzyl 2-O-acetyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-D-manno-2-octulopyranosonate (128678-23-9)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1016/0008-6215(90)84106-5

Reference yield:

Benzyl <2-(trimethylsilyl)ethyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-α-D-manno-2-octulopyranosid>onate (128678-22-8) → C35H35BrCl6O19 (128678-24-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / boron trifluoride etherate / CH₂Cl₂

2: titanium tetrabromide / CH₂Cl₂; ethyl acetate

With boron trifluoride diethyl etherate; titanium(IV) bromide; In dichloromethane; ethyl acetate;

DOI:10.1016/0008-6215(90)84106-5

upstream raw materials:

C₂₈H₄₂O₁₄Si

Chloroacetic anhydride

Downstream raw materials:

Benzyl 2-O-acetyl 7,8-bis-O-(chloroacetyl)-3-deoxy-4-O-<4,5,7,8-tetrakis-O-(chloroacetyl)-3-deoxy-α-D-manno-2-octulopyranosylono-1',5-lactone>-D-manno-2-octulopyranosonate

C₃₅H₃₅BrCl₆O₁₉