diethyl fluoronitromethylphosphonate

Base Information

• Chemical Name: diethyl fluoronitromethylphosphonate
• CAS No.: 1610542-23-8
• Molecular Formula: C₅H₁₁FNO₅P
• Molecular Weight: 215.118
• Mol file: 1610542-23-8.mol

Synonyms:diethyl fluoronitromethylphosphonate

Chemical Property of diethyl fluoronitromethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl fluoronitromethylphosphonate

There total 2 articles about diethyl fluoronitromethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

diethyl (nitromethyl)phosphonate (53753-37-0) → diethyl fluoronitromethylphosphonate (1610542-23-8)

Guidance literature:

diethyl (nitromethyl)phosphonate; With potassium hydroxide; In water; acetonitrile; at 0 - 25 ℃; for 2h; Inert atmosphere;

With Selectfluor; In water; acetonitrile; at 0 ℃; for 2h; Concentration; Inert atmosphere;

DOI:10.1002/chem.201303817

Reference yield: 12.0%

diethyl (nitromethyl)phosphonate (53753-37-0) → diethyl fluorophosphate (358-74-7) + diethyl fluoronitromethylphosphonate (1610542-23-8)

Guidance literature:

With sodium hydride; Selectfluor; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 - 25 ℃; Inert atmosphere;

DOI:10.1002/chem.201303817

Reference yield: 82.0%

diethyl fluoronitromethylphosphonate (1610542-23-8) + Phenyl vinyl ketone (768-03-6,26742-84-7) → diethyl (1-fluoro-1-nitro-4-oxo-4-phenylbutyl)phosphonate (1610542-45-4)

Guidance literature:

With diisopropylamine; In tetrahydrofuran; at -30 - 25 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201303817

upstream raw materials:

diethyl (nitromethyl)phosphonate

Downstream raw materials:

[(Z)-2-fluoro-2-nitroethenyl]benzene

(2-fluoro-2-nitrovinyl)benzene

1-chloro-4-[(Z)-2-fluoro-2-nitroethenyl]benzene

1-(2-fluoro-2-nitrovinyl)-4-chlorobenzene