ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

Base Information

Chemical Name:ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt
CAS No.:1444124-01-9
Molecular Formula:C₂HF₃O₂*C₂₀H₂₅N₃O₃
Molecular Weight:469.461
Hs Code.:

Synonyms:ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

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Chemical Property of ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

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Technology Process of ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

There total 3 articles about ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1444124-03-1
ethyl 1-{4-[(4-{[(tert-butoxy)carbonyl]amino}piperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate

: 1444124-01-9
ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 1444124-03-1
ethyl 1-{4-[(4-{[(tert-butoxy)carbonyl]amino}piperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate

: 76-05-1
trifluoroacetic acid

: 1444124-01-9
ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

Guidance literature:: In dichloromethane;

Reference yield:

: 18617-50-0
ethyl 6-hydroxypyridine-3-carboxylate

: 1444124-02-0
{4-[(4-{[(tert-butoxy)carbonyl]amino}piperidin-1-yl)methyl]phenyl}boronic acid

: 1444124-01-9
ethyl 1-{4-[(4-aminopiperidin-1-yl)methyl]phenyl}-6-oxo-1,6-dihydropyridine-3-carboxylate trifluoro acetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: copper diacetate; pyridine / dichloromethane

2: dichloromethane

With pyridine; copper diacetate; In dichloromethane;