Technology Process of (2S,3S)-N-1-(2-benzyloxy-3-fluoro-5-hexenyl)-O-benzylhydroxylamine
There total 1 articles about (2S,3S)-N-1-(2-benzyloxy-3-fluoro-5-hexenyl)-O-benzylhydroxylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium cyanoborohydride;
In
methanol;
for 1h;
Ambient temperature;
pH 3-4;
DOI:10.1016/0040-4020(95)00859-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) mercury(II) trifluoroacetate; 2.) NaHCO3, KCl; 3.) sodium borohydride, O2 / 1.) THF, rt, 2 h; 2.) THF/water, rt, 2 h; 3.) perfluorotributylamine/hexafluoroisopropanol, rt, 10 min
2: hydrogen / 10percent Pd/C / 24 h / 3040 Torr / Ambient temperature
With
sodium tetrahydroborate; potassium chloride; hydrogen; oxygen; mercury(II) trifluoroacetate; sodium hydrogencarbonate;
palladium on activated charcoal;
DOI:10.1016/0040-4020(95)00859-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) mercury(II) trifluoroacetate; 2.) NaHCO3, KCl; 3.) sodium borohydride, O2 / 1.) THF, rt, 2 h; 2.) THF/water, rt, 2 h; 3.) perfluorotributylamine/hexafluoroisopropanol, rt, 10 min
2: 68 percent / hydrogen / 10percent Pd/C / 24 h / 760 Torr / Ambient temperature
With
sodium tetrahydroborate; potassium chloride; hydrogen; oxygen; mercury(II) trifluoroacetate; sodium hydrogencarbonate;
palladium on activated charcoal;
DOI:10.1016/0040-4020(95)00859-7
