Technology Process of C12H12FN3
There total 5 articles about C12H12FN3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: isopropyl alcohol / 50 °C
2: caesium carbonate / tetrahydrofuran; isopropyl alcohol
3: hydrogenchloride / water
4: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 75 °C
5: ammonium acetate; ammonium hydroxide; zinc / ethanol; water / 80 °C
With
hydrogenchloride; hydroxylamine hydrochloride; ammonium acetate; caesium carbonate; ammonium hydroxide; sodium hydroxide; zinc;
In
tetrahydrofuran; ethanol; water; isopropyl alcohol;
2: Horner-Emmons condensation;
DOI:10.1016/j.bmcl.2011.08.071
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / water
2: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 75 °C
3: ammonium acetate; ammonium hydroxide; zinc / ethanol; water / 80 °C
With
hydrogenchloride; hydroxylamine hydrochloride; ammonium acetate; ammonium hydroxide; sodium hydroxide; zinc;
In
ethanol; water;
DOI:10.1016/j.bmcl.2011.08.071