2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

Base Information

Chemical Name:2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine
CAS No.:59761-78-3
Molecular Formula:C₁₄H₁₆ClN₅OS
Molecular Weight:337.833
Hs Code.:

2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-<i>N</i>-hydroxy-acetamidine

Synonyms:2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

Chemical Property:

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Technology Process of 2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

There total 5 articles about 2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56605-21-1
[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-acetonitrile

: dihydrochloric salt

: 59761-78-3
2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

Guidance literature:: With hydroxylamine hydrochloride; sodium carbonate; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 56605-37-9
2-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfanyl)-acetamide

: 59761-78-3
2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-diethylaniline / trichlorophosphate

2: sodium carbonate / ethanol; Petroleum ether

3: hydroxylamine hydrochloride; sodium carbonate / ethanol; N,N-dimethyl-formamide

With hydroxylamine hydrochloride; sodium carbonate; N,N-diethylaniline; In ethanol; N,N-dimethyl-formamide; Petroleum ether; trichlorophosphate;

Reference yield:

: 56-04-2,91795-77-6
6-methyl-2-thiouracil

: 59761-78-3
2-[4-(4-chloro-benzylamino)-6-methyl-pyrimidin-2-ylsulfanyl]-N-hydroxy-acetamidine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydrogencarbonate / ethanol; water

2: N,N-diethylaniline / trichlorophosphate

3: sodium carbonate / ethanol; Petroleum ether

4: hydroxylamine hydrochloride; sodium carbonate / ethanol; N,N-dimethyl-formamide

With hydroxylamine hydrochloride; sodium hydrogencarbonate; sodium carbonate; N,N-diethylaniline; In ethanol; water; N,N-dimethyl-formamide; Petroleum ether; trichlorophosphate;