2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

Base Information

Chemical Name:2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide
CAS No.:916810-72-5
Molecular Formula:C₁₂H₁₀F₆N₄O
Molecular Weight:340.228
Hs Code.:

Synonyms:2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

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Technology Process of 2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

There total 1 articles about 2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 864284-35-5
4-[(cyanomethyl)-(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

: 916810-72-5
2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

Guidance literature:: With hydroxylamine hydrochloride; sodium acetate; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

Reference yield: 90.0%

: 916810-72-5
2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

: 530-62-1
1,1'-carbonyldiimidazole

: 916809-07-9
4-[[(5-Oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)methyl](2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 120 ℃; for 0.333333h; Microwave irradiation;

Reference yield: 68.0%

: 916810-72-5
2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 916810-73-6
1,1-dimethylethyl 4-(3-{[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]methyl}-1,2,4-oxadiazol-5-yl)-1-piperidinecarboxylate

Guidance literature:: N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 0.75h;

2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]-N-hydroxyethanimidamide; In tetrahydrofuran; at 20 - 140 ℃; for 0.583333h; Microwave irradiation;