3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Base Information

Chemical Name:3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole
CAS No.:1269103-73-2
Molecular Formula:C₂₉H₂₇NO₅S
Molecular Weight:501.603
Hs Code.:

Synonyms:3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Suppliers and Price of 3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

There total 5 articles about 3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1269103-71-0
3-(3-ethoxy-1-hydroxyprop-2-yn-1-yl)-N-(phenylsulfonyl)-2-styrylindole

: 107-30-2
chloromethyl methyl ether

: 1269103-73-2
3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 50 ℃; for 12h; Inert atmosphere;
DOI:10.3987/COM-10-S(E)11

Reference yield:

: 1-(phenylsulfonyl)-2-styrylindole

: 1269103-73-2
3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Guidance literature:: Multi-step reaction with 3 steps

1.1: aluminum (III) chloride / dichloromethane / 3 h / -78 °C / Inert atmosphere

2.1: n-butyllithium; diethylamine / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 50 °C / Inert atmosphere

With aluminum (III) chloride; n-butyllithium; diethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.3987/COM-10-S(E)11

Reference yield:

: 1269103-70-9
N-(phenylsulfonyl)-2-styrylindole-3-carbaldehyde

: 1269103-73-2
3-[3-ethoxy-1-(methoxymethyloxy)prop-2-yn-1-yl]-N-(phenylsulfonyl)-2-styrylindole

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; diethylamine / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 50 °C / Inert atmosphere

With n-butyllithium; diethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.3987/COM-10-S(E)11