5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone

Base Information

• Chemical Name: 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone
• CAS No.: 191997-27-0
• Molecular Formula: C₁₉H₂₃Cl₂NO₃
• Molecular Weight: 384.303

Synonyms:5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone

Chemical Property of 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone

There total 2 articles about 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5S)-5-(3,4-Dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)tetrahydro-2(1H)-pyridinone (178310-89-9) + cyclopropylcarbinyl bromide (7051-34-5) → 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone (191997-27-0)

Guidance literature:

With potassium hydroxide; In water; dimethyl sulfoxide;

Reference yield:

(5S)-5-(3,4-Dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)tetrahydro-2(1H)-pyridinone (178310-89-9) → 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone (191997-27-0)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 16h;

DOI:10.1016/j.bmcl.2005.05.134

Reference yield:

5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone (191997-27-0) → [(S)-1-Cyclopropylmethyl-3-(3,4-dichloro-phenyl)-6-oxo-piperidin-3-yl]-acetaldehyde (178312-07-7)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1016/j.bmcl.2005.05.134

upstream raw materials:

(5S)-5-(3,4-Dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)tetrahydro-2(1H)-pyridinone

cyclopropylcarbinyl bromide

Downstream raw materials:

[(S)-1-Cyclopropylmethyl-3-(3,4-dichloro-phenyl)-6-oxo-piperidin-3-yl]-acetaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 191997-27-0 5(S)-1-Cyclopropylmethyl-5-(3,4-dichlorophenyl)-5-(1,3-dioxolan-2-ylmethyl)-2-piperidone

Send

Send

Metric Ton KG G Pound L ML

Send

Send