2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine

Base Information

Chemical Name:2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine
CAS No.:1339044-71-1
Molecular Formula:C₂₅H₂₂F₃N₇
Molecular Weight:477.492
Hs Code.:

Synonyms:2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine

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Chemical Property of 2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine

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Technology Process of 2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine

There total 1 articles about 2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 131747-62-1
3-(trifluoromethyl)-2-pyridinecarboxaldehyde

: 23491-49-8
2-amino-4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>aniline

: 1339044-71-1
2-(5'-(5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl)benzimidazol-2'-yl)-3-trifluoromethylpyridine

Guidance literature:: 3-(trifluoromethyl)-2-pyridinecarboxaldehyde; With sodium disulfite; In ethanol; water; at 40 - 50 ℃; for 0.0833333h;

2-amino-4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>aniline; In ethanol; water; for 16h; Reflux; Inert atmosphere;

With ammonia; In water; for 0.25h;