(S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile

Base Information

• Chemical Name: (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile
• CAS No.: 1172101-79-9
• Molecular Formula: C₂₇H₃₁NOSi
• Molecular Weight: 413.635
• Mol file: 1172101-79-9.mol

Synonyms:(S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile

Chemical Property of (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile

There total 1 articles about (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(S)-5-phenyl-3-hydroxypentanenitrile (125103-96-0) + tert-butylchlorodiphenylsilane (58479-61-1) → (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile (1172101-79-9)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.bmcl.2009.03.061

Reference yield: 71.0%

(S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile (1172101-79-9) → (S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanal (1172101-62-0)

Guidance literature:

(S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanenitrile; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 0.75h;

With water; Rochelle's salt; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2009.03.061

upstream raw materials:

(S)-5-phenyl-3-hydroxypentanenitrile

tert-butylchlorodiphenylsilane

Downstream raw materials:

(S)-(3-tert-butyldiphenylsilanyloxy)-5-phenylpentanal