4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one

Base Information

• Chemical Name: 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one
• CAS No.: 25919-09-9
• Molecular Formula: C₁₆H₂₀N₂O₄
• Molecular Weight: 304.346

Synonyms:4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one

Chemical Property of 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one

There total 2 articles about 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.1%

3-Acetyl-3-(3,4-dimethoxyphenyl)hexandisaeuredinitril (25924-26-9) → 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one (25919-09-9) + 3a-(3,4-dimethoxyphenyl)-7a-methyl-3,3a,4,5,7,7a-hexahydro-1H-pyrrolo<2,3-b>pyridine-2,6-dione + 5-amino-4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-methyl-4,5-dihydrofuran-2(3H)-one (25919-10-2) + 3-acetyl-5-cyano-3-(3,4-dimethoxyphenyl)pentanamide (97839-28-6)

Guidance literature:

With sulfuric acid; for 5h; Yields of byproduct given; Ambient temperature;

Reference yield:

→ 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one (25919-09-9)

Guidance literature:

V, 65percent H2SO4 (Addukt mit MeOH);

Reference yield: 89.0%

4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one (25919-09-9) → 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-methylenepyrrolidin-2-one (25919-08-8)

Guidance literature:

at 160 ℃; for 4h;

upstream raw materials:

3-Acetyl-3-(3,4-dimethoxyphenyl)hexandisaeuredinitril

Downstream raw materials:

4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-methylenepyrrolidin-2-one

5-amino-4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-methyl-4,5-dihydrofuran-2(3H)-one

7a-methyl-3a-(3,4-dimethoxyphenyl)-3,3a,4,5,7,7a-hexahydrofuro<2,3-b>pyridine-2,6-dione

3a-(3,4-dimethoxyphenyl)-2,3,3a,4,5,6-hexahydro-1H-indole-2,6-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 25919-09-9 4-(2-cyanoethyl)-4-(3,4-dimethoxyphenyl)-5-hydroxy-5-methylpyrrolidin-2-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send