N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

Base Information

Chemical Name:N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide
CAS No.:737828-48-7
Molecular Formula:C₁₈H₂₀ClN₃O₅S
Molecular Weight:425.893
Hs Code.:

Synonyms:N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

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Chemical Property of N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

Chemical Property:

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Technology Process of N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

There total 2 articles about N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56074-20-5
N-((tert-butyloxy)carbonyl)iminodiacetic acid

: 737828-48-7
N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

Guidance literature:: Multi-step reaction with 2 steps

1: EDCI / dimethylformamide / 1 h / 20 °C

2: 0.29 g / DMAP / dimethylformamide / 20 h

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.04.031

Reference yield:

: 2103-99-3
4-(4-chlorophenyl)-2-thiazolamine

: 56074-21-6
N-((tert-butyloxy)carbonyl)iminodiacetic acid anhydride

: 737828-48-7
N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

Guidance literature:: With dmap; In N,N-dimethyl-formamide; for 20h;
DOI:10.1016/j.bmc.2004.04.031

Reference yield: 69.0%

: 303-26-4
N-(4-chlorobenzhydryl)piperazine

: 737828-48-7
N-((tert-butyloxy)carbonyl)-N'-(2-(4-(4-chlorophenyl)thiazole))iminodiacetic acid monoamide

: 737828-57-8
(2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-{[4-(4-chloro-phenyl)-thiazol-2-ylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1016/j.bmc.2004.04.031