Technology Process of endo,endo-7,8-diphenylbicyclo<4.1.1>octa-2,4-diene
There total 10 articles about endo,endo-7,8-diphenylbicyclo<4.1.1>octa-2,4-diene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium carbonate; lithium chloride;
ground glass;
In
N,N,N,N,N,N-hexamethylphosphoric triamide;
at 110 ℃;
for 7h;
DOI:10.1021/jo00148a008
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 100 percent / m-chloroperbenzoic acid / CH2Cl2 / Ambient temperature
2: 77 percent / LDA / diethyl ether; hexane / Ambient temperature
3: 1.) methoxytriphenoxyphosphonium iodide, 2.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) HMPA, a) 60 deg C, 2 h, b) 105 deg C, 5 h, 2.) THF, RT, 36 h
With
methoxytriphenoxyphosphonium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide;
In
diethyl ether; hexane; dichloromethane;
DOI:10.1021/jo00148a008
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85 percent / benzene / 20 h / Heating
2: 1.) MeI, 2.) Zn, glacial acetic acid / 1.) glyme, 90 deg C, 5 h, 2.) THF, RT, overnight
3: 100 percent / m-chloroperbenzoic acid / CH2Cl2 / Ambient temperature
4: 77 percent / LDA / diethyl ether; hexane / Ambient temperature
5: 1.) methoxytriphenoxyphosphonium iodide, 2.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) HMPA, a) 60 deg C, 2 h, b) 105 deg C, 5 h, 2.) THF, RT, 36 h
With
methoxytriphenoxyphosphonium iodide; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; zinc; lithium diisopropyl amide; methyl iodide;
In
diethyl ether; hexane; dichloromethane; benzene;
DOI:10.1021/jo00148a008
