(-)-(S)-5-formyloxymethyloxol-3-en-2one

Base Information

• Chemical Name: (-)-(S)-5-formyloxymethyloxol-3-en-2one
• CAS No.: 85846-84-0
• Molecular Formula: C₆H₆O₄
• Molecular Weight: 142.111
• Mol file: 85846-84-0.mol

Synonyms:(-)-(S)-5-formyloxymethyloxol-3-en-2one

Chemical Property of (-)-(S)-5-formyloxymethyloxol-3-en-2one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(S)-5-formyloxymethyloxol-3-en-2one

There total 1 articles about (-)-(S)-5-formyloxymethyloxol-3-en-2one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

levoglucosenone (37112-31-5) → (5S)-5-(hydroxymethyl)-5H-furan-2-one (78508-96-0) + (-)-(S)-5-formyloxymethyloxol-3-en-2one (85846-84-0)

Guidance literature:

With dihydrogen peroxide; In water; at 50 ℃; for 10h; Inert atmosphere; Cooling with ice; Large scale;

DOI:10.1039/c8gc00553b

Reference yield:

(-)-(S)-5-formyloxymethyloxol-3-en-2one (85846-84-0) → (5S)-5-(hydroxymethyl)-5H-furan-2-one (78508-96-0)

Guidance literature:

With Amberlyst-15; In 1,4-dioxane; at 20 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; Time; Sealed tube;

DOI:10.1039/c3gc40267c

upstream raw materials:

levoglucosenone

Downstream raw materials:

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Refernces

• 1、 Bonneau, Guillaume,Peru, Aurélien A. M.,Flourat, Amandine L.,Allais, Florent. "Organic solvent- and catalyst-free Baeyer-Villiger oxidation of levoglucosenone and dihydrolevoglucosenone (Cyrene): A sustainable route to (: S)-γ-hydroxymethyl-α,β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone". supporting information. p. 2455 - 2458. Retrieved 2018/06/11.