8-Oxocoptisine

Base Information

Chemical Name:8-Oxocoptisine
CAS No.:19716-61-1
Molecular Formula:C19H13NO5
Molecular Weight:335.316
Hs Code.:
ChEMBL ID:CHEMBL3612189
DSSTox Substance ID:DTXSID901317158
Metabolomics Workbench ID:132806
Nikkaji Number:J690.353C
Wikidata:Q104397048
Mol file:19716-61-1.mol

Synonyms:8-oxocoptisine

Suppliers and Price of 8-Oxocoptisine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
8-Oxycoptisine ≥98%
10mg
$ 619.09

Arctom
8-Oxycoptisine
20mg
$ 518.00

Total 20 raw suppliers

Chemical Property of 8-Oxocoptisine

Chemical Property:

Melting Point:283-285℃
Boiling Point:617.5±55.0 °C(Predicted)
PKA:-1.62±0.20(Predicted)
PSA：58.92000
Density:1.61±0.1 g/cm3 (20 oC 760 Torr)
LogP:2.68200
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:335.07937252
Heavy Atom Count:25
Complexity:621

Purity/Quality:

≥98% ^*data from raw suppliers

8-Oxycoptisine ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): A poison by ingestion.
Hazard Codes:A poison by ingestion.

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C(=CC3=C(C2=O)C4=C(C=C3)OCO4)C5=CC6=C(C=C51)OCO6

Technology Process of 8-Oxocoptisine

There total 30 articles about 8-Oxocoptisine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 6020-18-4
coptisine chloride

: 19716-61-1
coptisinone

Guidance literature:: With sodium hydroxide; potassium hexacyanoferrate(III); In water; for 10h; Reflux;
DOI:10.1080/10286020.2014.932778

Reference yield: 56.0%

: 13-carboxaldehyde-8-oxocoptisine

: 19716-61-1
coptisinone

Guidance literature:: With Wilkinson's catalyst; diphenyl phosphoryl azide; In diethylene glycol dimethyl ether; at 160 ℃; for 12h; Inert atmosphere;
DOI:10.1002/chem.201601245

Reference yield: 53.0%

: 688006-48-6
7-(6-(2-hydroxyethyl)benzo[d][1,3]dioxol-5-yl)-[1,3]dioxolo[4,5-h]isoquinolin-9(8H)-one

: 19716-61-1
coptisinone

Guidance literature:: With potassium carbonate; p-toluenesulfonyl chloride; In N,N-dimethyl-formamide; at 100 ℃; for 4h;
DOI:10.1021/jo035836+