3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride

Base Information

Chemical Name:3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride
CAS No.:1026417-87-7
Molecular Formula:C₈H₆FNO₃S₂
Molecular Weight:247.271
Hs Code.:
DSSTox Substance ID:DTXSID601229176

Synonyms:3-isothiocyanato-4-methoxybenzenesulfonyl fluoride;1026417-87-7;DTXSID601229176

Suppliers and Price of 3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:246.97731356
Heavy Atom Count:15
Complexity:359

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)S(=O)(=O)F)N=C=S

Technology Process of 3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride

There total 1 articles about 3-Isothiocyanato-4-methoxybenzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 463-71-8
thiophosgene

: 498-74-8
3-Amino-4-methoxy benzene sulphonylfluoride

: 1026417-87-7
3-isothiocyanato-4-methoxybenzenesulfonyl fluoride

Guidance literature:: thiophosgene; 3-Amino-4-methoxy benzene sulphonylfluoride; In dichloromethane; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jm049538w

Reference yield:

: 681004-52-4
2-azido-1-(3'-bromophenyl)ethanone

: 1026417-87-7
3-isothiocyanato-4-methoxybenzenesulfonyl fluoride

: 681003-44-1
3-{[5-(3-bromophenyl)-1,3-oxazol-2-yl]amino}-4-methoxybenzenesulfonyl fluoride

Guidance literature:: With triphenylphosphine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm049538w

Reference yield:

: 1026417-87-7
3-isothiocyanato-4-methoxybenzenesulfonyl fluoride

: 681003-90-7
4-methoxy-3-({5-[3-(3-pyridinyl)phenyl]-1,3-oxazol-2-yl}amino)benzenesulfonyl fluoride

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine / CH₂Cl₂ / 2 h / 20 °C

2: 30 percent / tetrabutylammonium chloride; tetrakistriphenylphosphine palladium⁽⁰⁾ / acetonitrile / 100 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl-ammonium chloride; triphenylphosphine; In dichloromethane; acetonitrile; 2: Stille coupling;
DOI:10.1021/jm049538w