ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

Base Information

• Chemical Name: ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate
• CAS No.: 83022-04-2
• Molecular Formula: C₂₂H₃₂N₂O₇
• Molecular Weight: 436.505

Synonyms:ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

Chemical Property of ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

There total 22 articles about ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethyl p-<4-azido-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate (83022-03-1) → ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate (83022-04-2)

Guidance literature:

With quinoline; hydrogen; palladium on barium sulfate; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 12h; Ambient temperature;

DOI:10.1016/0008-6215(82)84035-4

Reference yield:

ethyl (E)-4-hydroxycinnamate (2979-06-8,7361-92-4,7362-39-2) → ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate (83022-04-2)

Guidance literature:

Multi-step reaction with 10 steps

1: AgClO₄, Ag₂CO₃, molecular sieve / CH₂Cl₂ / 24 h / Ambient temperature

2: Na/EtOH / CH₂Cl₂ / 0.5 h / Ambient temperature

3: 90 percent / H₂, quinoline / 5percent Pd-BaSO₄ / methanol / 20 h / 760 Torr / Ambient temperature

4: 87 percent / Et₃N / dioxane; H₂O / 16 h

5: pyridine

6: 60 percent / NaN₃ / hexamethylphosphoric acid triamide / 15 h / 80 °C

7: 95 percent / Na/EtOH / CH₂Cl₂ / 0.5 h / Ambient temperature

8: 96 percent / pyridine

9: 74 percent / NaI, NaBH₃CN / hexamethylphosphoric acid triamide / 16 h / 70 - 75 °C

10: 76 percent / H₂, quinoline / 5percent Pd-BaSO₄ / hexamethylphosphoric acid triamide / 12 h / Ambient temperature

With quinoline; sodium azide; molecular sieve; ethanol; hydrogen; silver perchlorate; sodium; sodium cyanoborohydride; triethylamine; silver carbonate; sodium iodide; palladium on barium sulfate; In 1,4-dioxane; pyridine; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; water;

DOI:10.1016/0008-6215(82)84035-4

Reference yield:

ethyl p-hydroxycinnamate trimethylsilyl ether (83021-95-8) → ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate (83022-04-2)

Guidance literature:

Multi-step reaction with 10 steps

1: AgClO₄, Ag₂CO₃, molecular sieve / CH₂Cl₂ / 24 h / Ambient temperature

2: Na/EtOH / CH₂Cl₂ / 0.5 h / Ambient temperature

3: 90 percent / H₂, quinoline / 5percent Pd-BaSO₄ / methanol / 20 h / 760 Torr / Ambient temperature

4: 87 percent / Et₃N / dioxane; H₂O / 16 h

5: pyridine

6: 60 percent / NaN₃ / hexamethylphosphoric acid triamide / 15 h / 80 °C

7: 95 percent / Na/EtOH / CH₂Cl₂ / 0.5 h / Ambient temperature

8: 96 percent / pyridine

9: 74 percent / NaI, NaBH₃CN / hexamethylphosphoric acid triamide / 16 h / 70 - 75 °C

10: 76 percent / H₂, quinoline / 5percent Pd-BaSO₄ / hexamethylphosphoric acid triamide / 12 h / Ambient temperature

With quinoline; sodium azide; molecular sieve; ethanol; hydrogen; silver perchlorate; sodium; sodium cyanoborohydride; triethylamine; silver carbonate; sodium iodide; palladium on barium sulfate; In 1,4-dioxane; pyridine; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; water;

DOI:10.1016/0008-6215(82)84035-4

upstream raw materials:

ethyl p-<4-azido-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

ethyl (E)-4-hydroxycinnamate

ethyl p-hydroxycinnamate trimethylsilyl ether

ethyl p-<4-azido-2-(tert-butoxycarbonyl)amino-2,4-dideoxy-α-D-glucopyranosyloxy>cinnamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 83022-04-2 ethyl p-<4-amino-2-(tert-butoxycarbonyl)amino-2,4,6-trideoxy-α-D-glucopyranosyloxy>cinnamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send