BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH

Base Information

• Chemical Name: BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH
• CAS No.: 1017964-65-6
• Molecular Formula: C₅₃H₆₅BrO₅Si₂
• Molecular Weight: 918.171
• Mol file: 1017964-65-6.mol

Synonyms:BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH

Chemical Property of BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH

There total 1 articles about BrCCCH₂CH₂CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH₂)4OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C56H74O5Si3 (1017964-64-5) → BrCCCH2CH2CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH2)4OH (1017964-65-6)

Guidance literature:

With N-Bromosuccinimide; silver nitrate; In acetone; at 23 ℃; for 12h;

DOI:10.1021/ja710485n

Reference yield: 89.0%

BrCCCH2CH2CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH2)4OH (1017964-65-6) + tri-n-butyl-tin hydride (688-73-3) → (n-Bu)3SnCHCHCH2CH2CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH2)4OH

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; treatment of bromoacetylene deriv. with 2.2 equiv. of tin compd. in THF in presence of palladium compd. and phosphine deriv. at 23°C for 1 h;

DOI:10.1021/ja710485n

Reference yield:

BrCCCH2CH2CH(p-methoxybenzyloxy)CH(tert-butyldiphenylsilyloxy)CHCHCH(tert-butyldiphenylsilyloxy)(CH2)4OH (1017964-65-6) → C53H63BrO5Si2 (1017964-84-9)

Guidance literature:

With sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 23 ℃; for 0.333333h;

DOI:10.1021/ja710485n

upstream raw materials:

C₅₆H₇₄O₅Si₃

Downstream raw materials:

C₅₃H₆₃BrO₅Si₂