Atrolactamide, (S)-

Base Information

Chemical Name:Atrolactamide, (S)-
CAS No.:136457-47-1
Molecular Formula:C₉H₁₁NO₂
Molecular Weight:165.192
Hs Code.:
UNII:MUD531MZPC
Nikkaji Number:J74.067E
Wikidata:Q27284233

Synonyms:Atrolactamide, D-;Atrolactamide, (S)-;UNII-MUD531MZPC;MUD531MZPC;136457-47-1;Benzeneacetamide, alpha-hydroxy-alpha-methyl-, (alphaS)-;(S)-atrolactamide;(?)-Atrolactamide;Q27284233;BENZENEACETAMIDE, .ALPHA.-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.S)-

Suppliers and Price of Atrolactamide, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Atrolactamide, (S)-

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:165.078978594
Heavy Atom Count:12
Complexity:175

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)(C(=O)N)O
Isomeric SMILES:C[C@](C1=CC=CC=C1)(C(=O)N)O

Technology Process of Atrolactamide, (S)-

There total 7 articles about Atrolactamide, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 136347-13-2
(S)-2-hydroxy-3-<(4-methylphenyl)sulfenyl>-2-propanamide

: 136457-47-1
(S)-2-hydroxy-2-phenylpropanamide

Guidance literature:: With nickel; In ethanol; for 2h; Ambient temperature;
DOI:10.1021/jo00052a044

Reference yield:

: 52154-24-2
(R)-p-tolylsulfinylacetophenone

: 136457-47-1
(S)-2-hydroxy-2-phenylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / ZnX₂ / toluene; tetrahydrofuran / 2 h / Ambient temperature

2: 82 percent / HCl(g) / diethyl ether / 1 h / 0 °C

3: 65 percent / Raney-Ni / ethanol / 2 h / Ambient temperature

With hydrogenchloride; nickel; In tetrahydrofuran; diethyl ether; ethanol; toluene;
DOI:10.1021/jo00052a044

Reference yield:

: 136347-09-6
(S₂,R_S)-2-hydroxy-3-<(4-methylphenyl)sulfinyl>-2-phenylpropanenitrile

: 136457-47-1
(S)-2-hydroxy-2-phenylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / HCl(g) / diethyl ether / 1 h / 0 °C

2: 65 percent / Raney-Ni / ethanol / 2 h / Ambient temperature

With hydrogenchloride; nickel; In diethyl ether; ethanol;
DOI:10.1021/jo00052a044