(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

Base Information

Chemical Name:(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine
CAS No.:357926-89-7
Molecular Formula:C₁₇H₁₈F₂N₄O₂
Molecular Weight:348.352
Hs Code.:

Synonyms:(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

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Technology Process of (2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

There total 2 articles about (2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 357926-87-5
(3R)-2,2-bis(4-fluorophenyl)-3-({[(methyloxy)methyl]oxy}methyl)aziridine

: 357926-89-7
(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

Guidance literature:: With sodium azide; ammonium chloride; In water; N,N-dimethyl-formamide; at 110 ℃; for 16h;
DOI:10.1021/jm900110t

Reference yield:

: 357926-89-7
(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

Guidance literature:

Reference yield: 61.0%

: 357926-89-7
(2R)-1-azido-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-2-propanamine

: 357926-34-2
(2R)-1,1-bis(4-fluorophenyl)-3-{[(methyloxy)methyl]oxy}-1,2-propanediamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 6h; under 760.051 Torr;
DOI:10.1021/jm900110t