N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Base Information

• Chemical Name: N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide
• CAS No.: 158098-89-6
• Molecular Formula: C₁₇H₂₃N₃O₂S
• Molecular Weight: 333.455
• Mol file: 158098-89-6.mol

Synonyms:N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Chemical Property of N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide

There total 2 articles about N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-heptyloxybenzoic acid methyl ester (67399-84-2) → N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂NNH₂*H₂O / ethanol / 8 h / Heating

2: HCl / ethanol / 18 h / Heating

3: Heating

With hydrogenchloride; hydrazine hydrate; In ethanol;

DOI:10.1515/znb-1997-1215

Reference yield:

4-heptyloxybenzoic hydrazide (64328-64-9) → N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-89-6)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / ethanol / 18 h / Heating

2: Heating

With hydrogenchloride; In ethanol;

DOI:10.1515/znb-1997-1215

Reference yield: 81.0%

N-[5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-yl]-acetamide (158098-89-6) → 5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-ylamine (158098-93-2)

Guidance literature:

With hydrogenchloride; In 2-methoxy-ethanol; for 18h; Heating;

DOI:10.1002/prac.19953370168

upstream raw materials:

4-heptyloxybenzoic acid methyl ester

4-heptyloxybenzoic hydrazide

Downstream raw materials:

5-(4-Heptyloxy-phenyl)-[1,3,4]thiadiazol-2-ylamine