N-phenyl-N-tosylmethacrylamide

Base Information

• Chemical Name: N-phenyl-N-tosylmethacrylamide
• CAS No.: 1356668-56-8
• Molecular Formula: C₁₇H₁₇NO₃S
• Molecular Weight: 315.393
• Mol file: 1356668-56-8.mol

Synonyms:N-phenyl-N-tosylmethacrylamide

Chemical Property of N-phenyl-N-tosylmethacrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-phenyl-N-tosylmethacrylamide

There total 2 articles about N-phenyl-N-tosylmethacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenyl toluenesulfonamide (68-34-8) + Methacryloyl chloride (920-46-7,26937-45-1) → N-phenyl-N-tosylmethacrylamide (1356668-56-8)

Guidance literature:

With triethylamine; In dichloromethane; at 25 ℃; for 12h;

DOI:10.1021/ja5115858

Reference yield:

aniline (62-53-3) + p-toluenesulfonyl chloride (98-59-9) + Methacryloyl chloride (920-46-7,26937-45-1) → N-phenyl-N-tosylmethacrylamide (1356668-56-8)

Guidance literature:

aniline; p-toluenesulfonyl chloride;

Methacryloyl chloride; With triethylamine; In dichloromethane;

DOI:10.1002/anie.201311241

Reference yield: 90.0%

di-tert-butyl peroxide (110-05-4) + N-phenyl-N-tosylmethacrylamide (1356668-56-8) → 2-methyl-N-phenyl-2-(p-tolyl)butanamide

Guidance literature:

With iron(III) sulfate; In fluorobenzene; at 115 ℃; for 8h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Sealed tube;

DOI:10.1016/j.tetlet.2016.07.105

upstream raw materials:

aniline

p-toluenesulfonyl chloride

Methacryloyl chloride

phenyl toluenesulfonamide

Downstream raw materials:

3-methyl-1-tosyl-3-(((trifluoromethyl)thio)methyl)indolin-2-one

2-methyl-2-(p-tolyl)-N-phenyl-3-tosylpropanamide

3-(diphenylphosphoryl)-2-methyl-N-phenyl-2-p-tolylpropanamide

3-azido-2-methyl-N-phenyl-2-p-tolylpropanamide