2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene

Base Information

• Chemical Name: 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene
• CAS No.: 1383536-25-1
• Molecular Formula: C₃₅H₃₅Br₅O₈
• Molecular Weight: 983.178
• Mol file: 1383536-25-1.mol

Synonyms:2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene

Chemical Property of 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene

There total 3 articles about 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

1-bromo-5-(3,4-dimethoxybenzyl)-2,3-dimethoxybenzene (1383535-99-6) + (2,3-dibromo-4,5-dimethoxyphenyl)methanol (4950-08-7) → 2,3-dibromo-1-(2-(3-bromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene (1383536-22-8) + 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene (1383536-25-1)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 ℃;

DOI:10.1002/ardp.201100373

Reference yield:

(3-bromo-4,5-dimethoxyphenyl)(3,4-dimethoxyphenyl)methanone (1383535-97-4) → 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene (1383536-25-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; trifluoroacetic acid / 0.5 h / 0 °C

2: aluminum (III) chloride / dichloromethane / 0 °C

With aluminum (III) chloride; sodium tetrahydroborate; trifluoroacetic acid; In dichloromethane; 2: Friedel Crafts alkylation;

DOI:10.1002/ardp.201100373

Reference yield:

3-bromo-4,5-dimethoxybenzoic acid (20731-48-0) → 2,3-dibromo-1-(2-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzyl)-4,5-dimethoxybenzene (1383536-25-1)

Guidance literature:

Multi-step reaction with 3 steps

1: polyphosphoric acid / 2 h / 80 °C

2: sodium tetrahydroborate; trifluoroacetic acid / 0.5 h / 0 °C

3: aluminum (III) chloride / dichloromethane / 0 °C

With aluminum (III) chloride; sodium tetrahydroborate; trifluoroacetic acid; In dichloromethane; 3: Friedel Crafts alkylation;

DOI:10.1002/ardp.201100373

upstream raw materials:

(3-bromo-4,5-dimethoxyphenyl)(3,4-dimethoxyphenyl)methanone

1-bromo-5-(3,4-dimethoxybenzyl)-2,3-dimethoxybenzene

(2,3-dibromo-4,5-dimethoxyphenyl)methanol

3-bromo-4,5-dimethoxybenzoic acid

Downstream raw materials:

3,4-dibromo-5-(3-bromo-2-(2-(2,3-dibromo-4,5-dihydroxybenzyl)-4,5-dihydroxybenzyl)-4,5-dihydroxybenzyl)benzene-1,2-diol