N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

Base Information

Chemical Name:N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide
CAS No.:1445853-68-8
Molecular Formula:C₃₂H₄₉NO₅
Molecular Weight:527.745
Hs Code.:

Synonyms:N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

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Chemical Property of N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

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Technology Process of N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

There total 3 articles about N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 1445854-32-9
methyl 7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanoate

: 1445853-68-8
N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

Guidance literature:: With hydroxylamine; potassium hydroxide; In tetrahydrofuran; methanol; water; at 0 - 20 ℃; for 48h;
DOI:10.1016/j.bmc.2015.05.011

Reference yield:

: 259733-96-5
3'-[4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl]-3'-[4-hydroxy-3-methylphenyl]pentane

: 54049-24-0
methyl 7-bromoheptanoate

: 1445853-68-8
N-hydroxy-7-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)heptanamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 12 h / Reflux

2: hydroxylamine; potassium hydroxide / methanol; tetrahydrofuran; water / 48 h / 0 - 20 °C

With hydroxylamine; potassium carbonate; potassium hydroxide; In tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1016/j.bmc.2015.05.011