1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Base Information

Chemical Name:1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide
CAS No.:1221569-04-5
Molecular Formula:C₃₁H₄₅ClN₆O₂
Molecular Weight:569.19
Hs Code.:

1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Synonyms:1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Suppliers and Price of 1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

There total 9 articles about 1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 423165-07-5
UK-408027

: 333985-70-9
1-acetyl-piperidine-4-carboxylic acid (3-chloro-4-methyl-phenyl)-(3-chloro-propyl)-amide

: 1221569-04-5
1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Guidance literature:: With triethylamine; In acetonitrile; for 24h; Reflux;

Reference yield:

: 76272-34-9
8-benzyl-8-azabicyclo[3.2.1] octan-3-one oxime

: 1221569-04-5
1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium; pentan-1-ol / 2 h / Reflux

2.1: sodium carbonate / dichloromethane; water / 2 h / 0 - 20 °C

3.1: phosphorus pentachloride / dichloromethane / 2 h / 10 - 20 °C / Cooling with ice

3.2: 10 - 20 °C

3.3: pH 12 / Cooling with ice

4.1: ammonium formate / palladium 10% on activated carbon / ethanol / 12 h / Reflux; Inert atmosphere

5.1: triethylamine / acetonitrile / 24 h / Reflux

With pentan-1-ol; phosphorus pentachloride; ammonium formate; sodium; sodium carbonate; triethylamine; palladium 10% on activated carbon; In ethanol; dichloromethane; water; acetonitrile;

Reference yield:

: 542-05-2
acetonedicarboxylic acid

: 1221569-04-5
1-acetyl-N-(3-chloro-4-methylphenyl)-N-(3-(3-exo-(3-isopropyl-5-methyl-4-hydro-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl)propyl)-4-piperidinylcarboxamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: hydrogenchloride; water / 1 h / Reflux

1.2: 6 h / 0 - 50 °C

1.3: pH 12

2.1: hydroxylamine hydrochloride; pyridine / ethanol / 18 h / Reflux

3.1: sodium; pentan-1-ol / 2 h / Reflux

4.1: sodium carbonate / dichloromethane; water / 2 h / 0 - 20 °C

5.1: phosphorus pentachloride / dichloromethane / 2 h / 10 - 20 °C / Cooling with ice

5.2: 10 - 20 °C

5.3: pH 12 / Cooling with ice

6.1: ammonium formate / palladium 10% on activated carbon / ethanol / 12 h / Reflux; Inert atmosphere

7.1: triethylamine / acetonitrile / 24 h / Reflux

With pyridine; hydrogenchloride; pentan-1-ol; phosphorus pentachloride; hydroxylamine hydrochloride; water; ammonium formate; sodium; sodium carbonate; triethylamine; palladium 10% on activated carbon; In ethanol; dichloromethane; water; acetonitrile;