1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

Base Information

Chemical Name:1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene
CAS No.:890839-64-2
Molecular Formula:C₁₀H₆ClF₃O
Molecular Weight:234.605
Hs Code.:
DSSTox Substance ID:DTXSID40705168
Wikidata:Q82637916

Synonyms:1-(3-chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene;890839-64-2;SCHEMBL15021728;DTXSID40705168;1-[(3-Chloroprop-2-yn-1-yl)oxy]-2-(trifluoromethyl)benzene

Suppliers and Price of 1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:234.0059270
Heavy Atom Count:15
Complexity:263

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(F)(F)F)OCC#CCl

Technology Process of 1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

There total 2 articles about 1-(3-Chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 890839-62-0
1-(prop-2-yn-1-yloxy)-2-(trifluoromethyl)benzene

: 890839-64-2
1-(3-chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

Guidance literature:: With N-chloro-succinimide; silver(I) acetate; In acetone; for 6h; Reflux;

Reference yield:

: 444-30-4
2-(trifluoromethyl)phenol

: 890839-64-2
1-(3-chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 96 h / 20 °C

2: N-chloro-succinimide; silver(I) acetate / acetone / 4 h / Reflux

With N-chloro-succinimide; silver(I) acetate; potassium carbonate; In acetone; acetonitrile;
DOI:10.1016/j.bmcl.2011.01.056

Reference yield:

: 890839-64-2
1-(3-chloroprop-2-ynyloxy)-2-(trifluoromethyl)benzene

: 890839-70-0,1228569-07-0
C₁₀H₁₀F₃NO

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 0.5 h / 20 °C

2: pyridine / 24 h / 20 °C

3: palladium 10% on activated carbon; ammonia; hydrogen / methanol / 1 h / 20 °C / 3102.97 Torr

With pyridine; sulfuric acid; palladium 10% on activated carbon; ammonia; hydrogen; In methanol;
DOI:10.1016/j.bmcl.2011.01.056