C₁₉H₁₇F₆N₃O₂S

Base Information

Chemical Name:C₁₉H₁₇F₆N₃O₂S
CAS No.:1422127-02-3
Molecular Formula:C₁₉H₁₇F₆N₃O₂S
Molecular Weight:465.419
Hs Code.:

C<sub>19</sub>H<sub>17</sub>F<sub>6</sub>N<sub>3</sub>O<sub>2</sub>S

Synonyms:C₁₉H₁₇F₆N₃O₂S

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Chemical Property of C₁₉H₁₇F₆N₃O₂S

Chemical Property:

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Technology Process of C₁₉H₁₇F₆N₃O₂S

There total 3 articles about C₁₉H₁₇F₆N₃O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32890-87-2
2,4-bis(trifluoromethyl)benzoic acid

: (5Z)-4-(methylamino)-5-(piperidin-4-ylmethylidene)-1,3-thiazol-2 (5H)-one dihydrochloride

: 1422127-02-3
C₁₉H₁₇F₆N₃O₂S

Guidance literature:: 2,4-bis(trifluoromethyl)benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 0.0833333h; Cooling with ice;

(5Z)-4-(methylamino)-5-(piperidin-4-ylmethylidene)-1,3-thiazol-2 (5H)-one dihydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;

Reference yield:

: 1422129-00-7
tert-butyl 4-{(Z)-[4-(methylamino)-2-oxo-1,3-thiazol-5(2H)-ylidene]methyl}piperidine-1-carboxylate

: 1422127-02-3
C₁₉H₁₇F₆N₃O₂S

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / methanol; tetrahydrofuran; ethyl acetate / 2 h / 80 °C

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / Cooling with ice

2.2: 20 °C / Cooling with ice

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 137076-22-3
tert butyl 4-formylpiperidine-1-carboxylate

: 1422127-02-3
C₁₉H₁₇F₆N₃O₂S

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium tert-butylate / ethanol / 8 h / 80 °C

2.1: hydrogenchloride / methanol; tetrahydrofuran; ethyl acetate / 2 h / 80 °C

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / Cooling with ice

3.2: 20 °C / Cooling with ice

With hydrogenchloride; potassium tert-butylate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; ethanol; ethyl acetate; N,N-dimethyl-formamide;