4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

Base Information

Chemical Name:4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid
CAS No.:105379-05-3
Molecular Formula:C₂₈H₃₀Cl₂N₂O
Molecular Weight:481.465
Hs Code.:

Synonyms:4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

Chemical Property:

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Technology Process of 4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

There total 4 articles about 4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 105378-77-6
1-<2-(4-Chlorphenylethyl)>-4-phenylpiperidin-4-yl-methanamin

: 25026-34-0
4-chlorophenacetyl chloride

: 105379-05-3
4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

Guidance literature:: In diethyl ether; for 0.25h;
DOI:10.1002/ardp.19863190606

Reference yield:

: 40481-13-8
4-phenyl-4-cyanopiperidine

: 105379-05-3
4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent

2: 75 percent / LiAlH₄ / tetrahydrofuran

3: 80 percent / diethyl ether / 0.25 h

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1002/ardp.19863190606

Reference yield:

: 105378-94-7
1-(4-Cyano-4-phenylpiperidin-1-yl)-2-(4-chlorphenyl)-1-ethanon

: 105379-05-3
4-Chlorphenyl-N-<1-<2-(4-chlorphenyl)-ethyl>-4-phenylpiperidin-4-yl-methyl>-acetamid

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / LiAlH₄ / tetrahydrofuran

2: 80 percent / diethyl ether / 0.25 h

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1002/ardp.19863190606