1-(4(t-butyl)phenyl)-2,2-dichloroethanone

Base Information

• Chemical Name: 1-(4(t-butyl)phenyl)-2,2-dichloroethanone
• CAS No.: 1426338-82-0
• Molecular Formula: C₁₂H₁₄Cl₂O
• Molecular Weight: 246.141
• Mol file: 1426338-82-0.mol

Synonyms:1-(4(t-butyl)phenyl)-2,2-dichloroethanone

Chemical Property of 1-(4(t-butyl)phenyl)-2,2-dichloroethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4(t-butyl)phenyl)-2,2-dichloroethanone

There total 2 articles about 1-(4(t-butyl)phenyl)-2,2-dichloroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-[4-(tert-butyl)phenyl]-2,2,2-trichloroethan-1-one (51326-37-5) → 1-(4(t-butyl)phenyl)-2,2-dichloroethanone (1426338-82-0)

Guidance literature:

1-[4-(tert-butyl)phenyl]-2,2,2-trichloroethan-1-one; With phenylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

With water-d2; In tetrahydrofuran;

DOI:10.1039/c3cc39147g

Reference yield:

tert-butylbenzene (253185-03-4,253185-04-5) → 1-(4(t-butyl)phenyl)-2,2-dichloroethanone (1426338-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane / 96 h / -30 °C / Inert atmosphere

2: phenylmagnesium bromide / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With aluminum (III) chloride; phenylmagnesium bromide; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c3cc39147g

upstream raw materials:

tert-butylbenzene

1-[4-(tert-butyl)phenyl]-2,2,2-trichloroethan-1-one