8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Base Information

Chemical Name:8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane
CAS No.:5309-15-9
Molecular Formula:C₁₅H₂₀O₃
Molecular Weight:248.322
Hs Code.:

Synonyms:8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Suppliers and Price of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Chemical Property:

Boiling Point:372.9±42.0 °C(Predicted)
Density:1.13±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

There total 8 articles about 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67019-46-9
8-(4-(trifluoromethoxy)phenyl)-1,4-dioxaspiro[4.5]dec-7-ene

: 5309-15-9
8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 3h;
DOI:10.1016/j.bmcl.2005.08.012

Reference yield:

: 67019-51-6
1-(4-methoxyphenyl)-1-hydroxycyclohexan-4-one ethylene ketal

: 5309-15-9
8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Guidance literature:: Multi-step reaction with 2 steps

1: TsOH / benzene / Heating

2: H₂ / Pd/C / ethyl acetate / 3 h

With hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In ethyl acetate; benzene;
DOI:10.1016/j.bmcl.2005.08.012

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 5309-15-9
8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane; water / 24 h / 100 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / 2585.81 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; sodium carbonate; In 1,4-dioxane; methanol; water; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2011.06.080