2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Base Information

Chemical Name:2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine
CAS No.:180992-32-9
Molecular Formula:C₁₅H₁₅ClN₂OS
Molecular Weight:306.816
Hs Code.:

Synonyms:2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Suppliers and Price of 2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

There total 7 articles about 2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 180340-61-8
2-Chloro-4-(4-nitrobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

: 180992-32-9
2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Guidance literature:: With hydrogenchloride; iron; In acetic acid;
DOI:10.1016/S0960-894X(00)00084-6

Reference yield:

: 13414-95-4
4-keto-4,5,6,7-tetrahydrothianaphthene

: 180992-32-9
2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Guidance literature:: Multi-step reaction with 7 steps

1: 99 percent / NH₂OH*HCl; aq. NaOAc / ethanol

2: 92 percent / pyridine

3: 60 percent / aq. KOAc / ethanol

4: 91 percent / BH₃*S(CH₃)2 / tetrahydrofuran

5: Et₃N / CH₂Cl₂

6: NCS

7: Fe; 6N aq. HCl / acetic acid

With pyridine; hydrogenchloride; N-chloro-succinimide; dimethylsulfide borane complex; hydroxylamine hydrochloride; potassium acetate; sodium acetate; iron; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; acetic acid; 1: Condensation / 2: Tosylation / 3: Rearrangement / 4: Reduction / 5: Acylation / 6: Chlorination / 7: Reduction;
DOI:10.1016/S0960-894X(00)00084-6

Reference yield:

: 19995-19-8,79222-03-0,79222-05-2
4,5,6,7-tetrahydro-4-oxobenzo[b]thiophene oxime

: 180992-32-9
2-chloro-4-(4-aminobenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine

Guidance literature:: Multi-step reaction with 6 steps

1: 92 percent / pyridine

2: 60 percent / aq. KOAc / ethanol

3: 91 percent / BH₃*S(CH₃)2 / tetrahydrofuran

4: Et₃N / CH₂Cl₂

5: NCS

6: Fe; 6N aq. HCl / acetic acid

With pyridine; hydrogenchloride; N-chloro-succinimide; dimethylsulfide borane complex; potassium acetate; iron; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; acetic acid; 1: Tosylation / 2: Rearrangement / 3: Reduction / 4: Acylation / 5: Chlorination / 6: Reduction;
DOI:10.1016/S0960-894X(00)00084-6