1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

Base Information

Chemical Name:1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone
CAS No.:1028459-47-3
Molecular Formula:C₂₂H₁₅ClF₂N₂O₂
Molecular Weight:412.823
Hs Code.:

Synonyms:1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

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Chemical Property of 1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

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Technology Process of 1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

There total 2 articles about 1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1028459-73-5
6-chloro-1-(4-fluorophenyl)-1H-indazol-5-ol

: 459-03-0
4-fluorophenyl acetone

: 1028459-47-3
1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

Guidance literature:: 4-fluorophenyl acetone; With bromine; In dichloromethane; for 0.5h;

6-chloro-1-(4-fluorophenyl)-1H-indazol-5-ol; With potassium carbonate; In tetrahydrofuran; dichloromethane; for 4h;

Reference yield:

: 1028459-73-5
6-chloro-1-(4-fluorophenyl)-1H-indazol-5-ol

: 71827-48-0
α-bromo-(4-fluorophenyl)acetone

: 1028459-47-3
1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

Guidance literature:: With potassium carbonate; In tetrahydrofuran; for 4h;

Reference yield:

: 1028459-47-3
1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone

: (1RS,2RS)-1-[6-chloro-1-(4-fluorophenyl)indazol-5-yl]oxy-1-(4-fluorophenyl)propan-2-amine

: (1RS,2SR)-1-[6-chloro-1-(4-fluorophenyl)indazol-5-yl]oxy-1-(4-fluorophenyl)propan-2-amine

Guidance literature:: 1-{[6-chloro-1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(4-fluorophenyl)acetone; With CH₃BN^(1-)*C₁₀H₁₅NPol⁽¹⁺⁾; ammonium acetate; In methanol; at 140 ℃; for 0.166667h; not specified Microwave irradiation;

With sodium hydrogencarbonate; In dichloromethane;