Technology Process of 2-<3-hydroxy-2-(3-hydroxypropyl)phenoxy>benzoic acid ethyl ester
There total 7 articles about 2-<3-hydroxy-2-(3-hydroxypropyl)phenoxy>benzoic acid ethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 43 percent / copper bronze, potassium carbonate / pyridine / 144 h / Heating
2: 36 percent / KOH / ethanol; H2O / 18 h / Heating
3: 1.) pyridine hydrochloride, 2.) water / 1.) 180-185 deg C, 3 h, 2.) RT, 18 h
4: 84 percent / conc. H2SO4 / 48 h / Heating
5: 93 percent / potassium carbonate, potassium iodide / butan-2-one / 96 h / Heating
6: 2.) 0.5 M 9-BBN, 3.) sodium acetate, H2O2
With
potassium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; sulfuric acid; water; dihydrogen peroxide; sodium acetate; pyridine hydrochloride; copper; potassium carbonate; potassium iodide;
In
pyridine; ethanol; water; butanone;
DOI:10.1021/jm00064a006
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 43 percent / copper bronze, potassium carbonate / pyridine / 144 h / Heating
2: 36 percent / KOH / ethanol; H2O / 18 h / Heating
3: 1.) pyridine hydrochloride, 2.) water / 1.) 180-185 deg C, 3 h, 2.) RT, 18 h
4: 84 percent / conc. H2SO4 / 48 h / Heating
5: 93 percent / potassium carbonate, potassium iodide / butan-2-one / 96 h / Heating
6: 2.) 0.5 M 9-BBN, 3.) sodium acetate, H2O2
With
potassium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; sulfuric acid; water; dihydrogen peroxide; sodium acetate; pyridine hydrochloride; copper; potassium carbonate; potassium iodide;
In
pyridine; ethanol; water; butanone;
DOI:10.1021/jm00064a006
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) pyridine hydrochloride, 2.) water / 1.) 180-185 deg C, 3 h, 2.) RT, 18 h
2: 84 percent / conc. H2SO4 / 48 h / Heating
3: 93 percent / potassium carbonate, potassium iodide / butan-2-one / 96 h / Heating
4: 2.) 0.5 M 9-BBN, 3.) sodium acetate, H2O2
With
9-borabicyclo[3.3.1]nonane dimer; sulfuric acid; water; dihydrogen peroxide; sodium acetate; pyridine hydrochloride; potassium carbonate; potassium iodide;
In
butanone;
DOI:10.1021/jm00064a006