N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene

Base Information

• Chemical Name: N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene
• CAS No.: 114396-97-3
• Molecular Formula: C₁₈H₁₉NO₂
• Molecular Weight: 281.354
• Mol file: 114396-97-3.mol

Synonyms:N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene

Chemical Property of N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene

There total 2 articles about N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Allyl-cyclohepta-2,4,6-trienyl-amine (114396-95-1) + benzyl chloroformate (501-53-1,94274-21-2) → N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene (114396-97-3)

Guidance literature:

With sodium hydroxide; In dichloromethane; water; at 0 ℃; for 2h;

DOI:10.1021/jo00247a001

Reference yield:

tropylium tetrafluoroborate (27081-10-3) → N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene (114396-97-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium bicarbonate / diethyl ether; tetrahydrofuran; H₂O / 24 h / 25 °C

2: 74 percent / sodium hydroxide / CH₂Cl₂; H₂O / 2 h / 0 °C

With sodium hydroxide; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; dichloromethane; water;

DOI:10.1021/jo00247a001

Reference yield: 56.0%

N-(benzyloxycarbonyl)-N-allyl-7-aminocyclohepta-1,3,5-triene (114396-97-3) → N-(benzyloxycarbonyl)-N-allyl-3-aminocyclohepta-1,3,5-triene (114397-05-6) + N-(benzyloxycarbonyl)-3-azatricyclo<5.3.1.04,10>undeca-5,8-diene (114397-04-5)

Guidance literature:

In octane; for 16h; Heating;

DOI:10.1021/jo00247a001

upstream raw materials:

Allyl-cyclohepta-2,4,6-trienyl-amine

benzyl chloroformate

tropylium tetrafluoroborate

Downstream raw materials:

N-(benzyloxycarbonyl)-N-allyl-3-aminocyclohepta-1,3,5-triene

N-(benzyloxycarbonyl)-3-azatricyclo<5.3.1.0^4,10>undeca-5,8-diene