7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine

Base Information

Chemical Name:7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine
CAS No.:6980-13-8
Molecular Formula:C₁₁H₁₂ClN₃O₄
Molecular Weight:285.687
Hs Code.:
Mol file:6980-13-8.mol

Synonyms:7-chloro-3-β-D-ribofuranosyl-3H-imidazo<4,5-b>pyridine;7-Chlor-3-β-D-ribofuranosylimidazo<4,5-b>pyridin;1-(7-chloro-imidazo[4,5-b]pyridin-3-yl)-β-D-1-deoxy-ribofuranose;(2R,3R,4S,5R)-2-(7-Chloro-imidazo[4,5-b]pyridin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol;

Suppliers and Price of 7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine

Chemical Property:

Refractive Index:1.6000 (estimate)
PSA：100.63000
Density:1.5483 (rough estimate)
LogP:-0.30380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s): 3
Hazard Codes: 3:;
Safety Statements:Poison by intraperitoneal route. Mildly toxic by ingestion. Human blood effects by intravenous"> − and NOx." target="_blank">Poison by intraperitoneal route. Mildly toxic by ingestion. Human blood effects by intravenous

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine

There total 6 articles about 7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 34311-43-8
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(7-chloro-3H-imidazo[4,5-b]pyridin-3-yl)tetrahydrofuran-3,4-diyl diacetate

: 6980-13-8
7-chloro-3-β-D-ribofuranosyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: With ammonia; In methanol; Ambient temperature;

Reference yield:

: 81356-78-7
1-Trimethylsilanyl-1H-imidazo[4,5-b]pyridine 4-oxide

: 6980-13-8
7-chloro-3-β-D-ribofuranosyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 68.1 percent / SnCl₄ / acetonitrile / 5 h / Ambient temperature

2: POCl₃, molecular sieves 4A / CHCl₃ / 18 h / 30 °C

3: 65.3 percent / HgBr₂, TAR / toluene / 24 h / Heating

4: 90 percent / NH₃ / methanol / Ambient temperature

With 4 A molecular sieve; 4-(thiazol-2-ylazo)resorcinol; ammonia; tin(IV) chloride; mercury dibromide; trichlorophosphate; In methanol; chloroform; toluene; acetonitrile;

Reference yield:

: 81356-79-8
1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-imidazo<4,5-b>pyridine 4-oxide

: 6980-13-8
7-chloro-3-β-D-ribofuranosyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃, molecular sieves 4A / CHCl₃ / 18 h / 30 °C

2: 65.3 percent / HgBr₂, TAR / toluene / 24 h / Heating

3: 90 percent / NH₃ / methanol / Ambient temperature

With 4 A molecular sieve; 4-(thiazol-2-ylazo)resorcinol; ammonia; mercury dibromide; trichlorophosphate; In methanol; chloroform; toluene;