2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide

Base Information

• Chemical Name: 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide
• CAS No.: 408496-92-4
• Molecular Formula: C₃₄H₄₃BrN₂O₁₁
• Molecular Weight: 735.626
• Mol file: 408496-92-4.mol

Synonyms:2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide

Chemical Property of 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide

There total 1 articles about 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,3,4-tetra-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α/β-L-galacto-decopyranose → 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide (408496-92-4)

Guidance literature:

With Acetyl bromide; water; acetic anhydride; In dichloromethane; acetic acid; at 20 ℃; for 2h;

DOI:10.1081/CAR-100108277

Reference yield: 43.0%

triethylamine (121-44-8) + 2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide (408496-92-4) → Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-[5-(4-benzoylamino-2,5-diethoxy-phenylcarbamoyl)-pentyl]-2-phosphonooxy-tetrahydro-pyran-3-yl ester; compound with triethyl-amine

Guidance literature:

2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide; With 4 A molecular sieve; tetra-n-butyl-ammonium phosphate; In acetonitrile; at 0 - 20 ℃;

triethylamine; In methanol; ethyl acetate;

DOI:10.1081/CAR-100108277

Reference yield:

2,3,4-tri-O-acetyl-10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-α-L-galacto-decopyranosyl bromide (408496-92-4) → bis(triethylammonium) 10-(4-benzamido-2,5-diethyloxyphenylaminocarbonyl)-6,7,8,9,10-pentadeoxy-β-L-galacto-decopyranos-1-yl phosphate

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrabutylammonium phosphate; molecular sieves 4 Angstroem / acetonitrile / 0 - 20 °C

1.2: 43 percent / ethyl acetate; methanol

2.1: cyclohexylamine / methanol / 2 h / Heating

2.2: 60 percent / Dowex 50-X₈ (Et₃NH⁺) / H₂O

With 4 A molecular sieve; cyclohexylamine; tetra-n-butyl-ammonium phosphate; In methanol; acetonitrile;

DOI:10.1081/CAR-100108277