4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride

Base Information

• Chemical Name: 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride
• CAS No.: 1409990-31-3
• Molecular Formula: C₁₂H₁₅ClN₂O*ClH
• Molecular Weight: 275.178
• Mol file: 1409990-31-3.mol

Synonyms:4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride

Chemical Property of 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride

There total 1 articles about 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-methylpiperazin-1-yI)benzoic acid (354813-15-3,86620-62-4) → 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride (1409990-31-3)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 6.5h; Heating / reflux;

Reference yield:

tert-butyl 3-amino-1H-thieno[2,3-c]pyrazole-5-carboxylate (656235-18-6) + 4-(4-methylpiperazin-1-yl)benzoyl chloride hydrochloride (1409990-31-3) → 4-(4-methylpiperazin-1-yl)benzoic anhydride + tert-butyl 1-[4-(4-methylpiperazin-1-yl)benzoyl]-3-{[4-(4-methylpiperazin-1-yl)benzoyl]amino}-1H-thieno[2,3-c]pyrazole-5-carboxylate (862559-69-1) + 4-(4-methylpiperazin-1-yI)benzoic acid (354813-15-3,86620-62-4)

Guidance literature:

With pyridine; In dichloromethane; at 5 - 20 ℃; for 78h;

upstream raw materials:

4-(4-methylpiperazin-1-yI)benzoic acid

Downstream raw materials:

tert-butyl 1-[4-(4-methylpiperazin-1-yl)benzoyl]-3-{[4-(4-methylpiperazin-1-yl)benzoyl]amino}-1H-thieno[2,3-c]pyrazole-5-carboxylate

4-(4-methylpiperazin-1-yI)benzoic acid